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Neither cervical dilatation nor anaesthesia was required, and the probe could be easily introduced through the cervix into the endometrial cavity in all patients. Moreover, it was possible to obtain finer image quality of very small endometrial interfacial and internal textures with intrauterine sonography than with transvaginal sonography.

In proliferative phase (10.7 ± 1.4 days) (oestradiol, 130.9 ± 41.8 pg/ml; progesterone, 0.61 ± 0.19 ng/ml), endometrium appeared as a leaflet pattern with hypo-echoic functionalis surrounded by minimal hyperechoic basalis and echogenic endometrial interface by transvaginal sonography (Figure 1a).

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After intrauterine saline infusion, the smooth interface of the lumen was visualized with both transvaginal and intrauterine images, but intrauterine sonography depicted it more clearly and finely than transvaginal sonography (Figure 1c,d).

Intrauterine sonography characterized anterior and posterior endometrial layers as different echogenic patterns with slightly irregular interface of the endometrium (Figure 2b), but not by transvaginal sonography (Figure 2c), but not visualized using transvaginal sonography (Figure 3b Whole-exome sequencing identifies a GREB1L variant in a three-generation family with Müllerian and renal agenesis: a novel candidate gene in Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome.

Endometrial assessment has been performed usually by endometrial biopsy [1].

However, such as invasive method is not acceptable when evaluating endometrial receptivity in order not to damage the endometrium.

The subjective assessment of overall image clarity was compared between transvaginal and intrauterine sonography.

Hormonal measurements such as oestradiol and progesterone were also performed at each examination in each patient. Most endometrial textures in both proliferative and secretory phases were easier to view with intrauterine rather than transvaginal sonography, and this was especially true with an intrauterine saline infusion technique.

If you have endometrial cancer or are close to someone who does, knowing what to expect can help you cope.

Here you can find out all about endometrial cancer, including risk factors, symptoms, how it is found, and how it is treated.

Endometrial vascularization increases during follicular phase peaking 2–3 days before ovulation, decreasing thereafter and increasing again during mid and late luteal phase.

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